The Best Over-the-Counter Eye Drops for Dry Eye Symptoms and Allergy Relief

Mild to Moderate Dry Eyes

Dry eye symptoms can range from occasional dryness to ongoing irritation. Mild to moderate dry eye often feels like a gritty sensation, occasional burning or stinging, and intermittent blurry vision. Common causes include dry air, air conditioning, extended reading, or natural tear film instability. For these everyday dry eye concerns, two OTC products provide dependable relief. 

Refresh Optive® GEL Drops

If your dryness is more persistent than occasional discomfort, Refresh Optive® GEL Drops are an excellent choice. These gel-based drops can be used day or night, forming a soothing protective layer over the eye’s surface. Their thicker texture delivers long-lasting moisture, helping to ease moderate dry eye symptoms. Whether coping with dry indoor air or seasonal allergies, Refresh Optive® GEL Drops offer gentle, all-day comfort to keep your eyes feeling refreshed. 

Refresh Relieva® PF 

When mild to moderate dryness flares during the day, Refresh Relieva® PF is a preservative-free option made specifically for daytime use. These drops lock in moisture and help prevent further irritation, making them ideal for active individuals seeking effective relief without the stinging sensation some eye drops cause. The preservative-free formula is gentle on sensitive eyes and provides sustained lubrication so you can stay comfortable without frequent rubbing or reaching for tissues. 

Screen-Induced Dry Eyes 

With increased time spent on computers, tablets, smartphones, and TVs, digital eye strain has become widespread. Staring at screens reduces your blink rate, causing tears to evaporate faster than they can be replaced. This often results in dry, tired eyes that burn, itch, or feel gritty—especially when you need your vision to be sharpest. 

Refresh Digital® PF

Refresh Digital® PF is specially formulated to address the rapid dryness caused by extended screen time. These preservative-free drops are ideal for use during or immediately after long sessions on digital devices. They mimic natural tears to quickly restore moisture and provide relief without blurring your vision. The lightweight formula soothes irritation, helping you blink naturally and return to your screen with clear, comfortable eyes. 

Moderate to Severe Dry Eyes

If your eyes feel very dry, especially overnight, finding effective relief during sleep is crucial to avoid waking with irritation. Moderate to severe dry eye may result from chronic tear-film instability, certain medications, or environmental factors like low humidity. Without adequate lubrication throughout the night, your eyes can become red, scratchy, and uncomfortable by morning. 

Refresh PM®

Refresh PM® is designed specifically for nighttime use, forming a protective, slow-release barrier that locks in moisture all night long. Its thick, ointment-like consistency stays on the eye longer than typical drops, offering continuous hydration and soothing relief for severe dry eye symptoms. Applying Refresh PM® before bed helps you wake up with refreshed, comfortable eyes, reducing morning dryness and minimizing the need for heavy daytime drops. 

Allergy Relief

During allergy season, itchy, watery eyes caused by pollen, dust, or pet dander can make it hard to concentrate or enjoy outdoor activities. Rather than constantly rubbing or rinsing, antihistamine eye drops target the chemicals responsible for allergic reactions to provide relief. 

Pataday®

Pataday® is a doctor-recommended, effective solution for all-day allergy relief. Many users apply it once in the morning and again in the evening to maintain consistent comfort. It blocks histamine—the main cause of itching and tearing during allergies. With just one application providing up to 24 hours of protection, Pataday® helps keep your eyes calm and clear, so you can enjoy your time outdoors without the urge to rub or wipe tears away. 

Choosing the Right OTC Eye Drops & When to See an Eye Care Professional

Finding the most effective eye drops begins with understanding what’s causing your symptoms. For occasional dryness, grittiness, or brief blurry vision, mild lubricants like Refresh Relieva® PF for daytime use or thicker formulas such as Refresh Optive® GEL for all-day comfort can provide relief. If dryness occurs after long periods at computers or gaming devices, Refresh Digital® PF delivers fast-acting relief designed for the reduced blink rate associated with screen use. For severe dryness that worsens overnight, Refresh PM® offers a protective moisture barrier to help you wake up feeling refreshed. And if itchy, watery eyes are your main concern during allergy season, Pataday® provides up to 24 hours of antihistamine relief with just one or two daily applications.

Once you select the product that fits your symptoms, it’s important to follow the instructions closely. Always wash your hands before applying drops, avoid touching the bottle tip to your eyes or skin, and keep the cap tightly closed to avoid contamination. Pay attention to preservative warnings, especially if your eyes are sensitive, and discard bottles after their expiration date.

While OTC eye drops can effectively relieve many mild to moderate symptoms, persistent or worsening issues require professional evaluation. If you experience increasing redness, pain, discharge, light sensitivity, or vision changes that don’t improve after a week of proper use, schedule a consultation at Grene Vision Group. Our doctors can identify underlying conditions like blepharitis, infections, or other serious eye concerns and recommend the right treatments to restore your clear, comfortable vision.